My clinical training specialty is in Infectious Diseases & Microbiology, and during this time I developed an interest in better understanding immunity to tuberculosis, a pathogen that has circulated in the human population for centuries, and yet still has a significant impact on morbidity and mortality worldwide.
In 2013 I was awarded a Wellcome Trust Postdoctoral Clinical Research Fellowship to study correlates of protection to tuberculosis, making use of both human in vivo challenge models and in vitro models of macrophage-tuberculosis interaction. The project will largely be based in the laboratory of Dr Mahdad Noursadeghi (UCL) and will involve recruitment of individuals infected with tuberculosis both in the UK and in Peru, in collaboration with Professor David Moore (London School of Hygiene and Tropical Medicine).
My work touches on two core themes in the group, namely investigating human immune responses to tuberculosis infection and improving comparative analysis of whole genome transcriptional data.
My latest list of publications can be found here.